Comprar 99.38% Purity Laboratory Tested Procainamide Hydrochloride Powder Raw Local Anesthetic Material With Discreet Shipping Fast Delivery
Procainamide Hydrochloride Powder Specification
| Product name |
Procainamide hydrochloride |
| CAS No. |
614-39-1 |
Outer Packing |
25KG/DRUM |
| Production date |
2019.01.08 |
Validade |
2021.01.07 |
| Standard adopted |
USP 38 |
| Items of analysis |
Especificação |
Resultados |
| Aparência |
A white or almost white crystalline |
Complies |
| Identificação |
A.B in pass |
Complies |
| Ponto de fusão |
165°~169° |
166°~169° |
| Solution trasparence |
50mg/mL colourless liquid |
colourless liquid |
| Organic volatile impurities |
Atende aos requisitos |
Complies |
| Limit of free p-aminobenzoic acid |
≤0.1% |
0.05% |
| USP Reference standards |
USP Procainamide Hydrochoride RS. |
Complies |
| Perda ao secar |
≤0.3% |
0.12% |
| Resíduo de ignição |
≤0.1% |
0.03% |
| Heavy Metals(ppm) |
≤0.002% |
5ppm |
| Ensaio |
98.0~102.0% |
99.38% |
| Conclusão |
Qualified |
Procainamide Hydrochloride Description
Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydrochloride reversibly binds to and blocks activated (open) voltage-gated sodium channels, thereby blocks the influx of sodium ions into the cell, which leads to an increase in threshold for excitation and inhibit depolarization during phase 0 of the action potential.
além do que, além do mais, the effective refractory period (ERP), action potential duration (APD), and ERP/APD ratios are increased, resulting in decreased impulse conduction velocity. The lasting action potential may also be due to blockage of outward K+ currents. The result is a decrease in automaticity, increase in refractory period and slowing of impulse conduction.
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