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99.38% Purity Procainamide Hydrochloride Powder | Local Anesthetic

Assay: 99.38%by HPLC
Standard: USP38
Minimum order quantity(MOQ): 10g
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Buy 99.38% Purity Laboratory Tested Procainamide Hydrochloride Powder Raw Local Anesthetic Material With Discreet Shipping Fast Delivery


Procainamide Hydrochloride Powder Specification

Product name Procainamide hydrochloride
CAS No. 614-39-1 Outer Packing 25KG/DRUM
Production date 2019.01.08 Shelf life 2021.01.07
Standard adopted USP 38
Items of analysis Specification Results
Appearance A white or almost white crystalline Complies
Identification A.B in pass Complies
Melting Point 165°~169° 166°~169°
Solution trasparence 50mg/mL colourless liquid colourless liquid
Organic volatile impurities Meets the requirements Complies
Limit of free p-aminobenzoic acid ≤0.1% 0.05%
USP Reference standards USP Procainamide Hydrochoride RS. Complies
Loss on drying ≤0.3% 0.12%
Residue on ignition ≤0.1% 0.03%
Heavy Metals(ppm) ≤0.002% 5ppm
Assay 98.0~102.0% 99.38%
Conclusion Qualified


Procainamide Hydrochloride Description

Procainamide Hydrochloride is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analog of procaine. Procainamide hydrochloride reversibly binds to and blocks activated (open) voltage-gated sodium channels, thereby blocks the influx of sodium ions into the cell, which leads to an increase in threshold for excitation and inhibit depolarization during phase 0 of the action potential.

In addition, the effective refractory period (ERP), action potential duration (APD), and ERP/APD ratios are increased, resulting in decreased impulse conduction velocity. The lasting action potential may also be due to blockage of outward K+ currents. The result is a decrease in automaticity, increase in refractory period and slowing of impulse conduction.

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