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Tamoxifen Citrate is a SERM that acts as both antagonist and agonist in relation to the estrogen hormone. It is an anti-estrogen in that it binds to estrogen receptors in certain parts of the body, particularly in the mammary tissue. This action prevents estrogen from acting on its originally intended point of binding. This makes Tamoxifen Citrate valuable to breast cancer patients as breast cancer feeds off of estrogen. And it’s valuable to steroid users as increased estrogen levels can bind to the mammary tissue and lead to gynecomastia.
Tamoxifen Citrate is most often referred to as “Nolvadex” by Bodybuilders. Nolvadex is not a steroid, rather a selective Estrogen blocker. While Nolvadex doesn’t prevent the build-up of Estrogen in the body, it does prevent it from acting on certain receptors, most notably, those located in the nipples. This has obvious benefits to bodybuilders, because this is the area in which “gyno” occurs during the use of aromatizing steroids such as testosterone.
|Identification||IR, UV conform||Conform|
|Loss on drying||≤0.5ml||0.21ml|
|Residue on ignition||Not more than 0.2%||0.07ml|
|Iron||Not more than 0.005%||0.0017%|
|Heavy metals||Not more than 0.001%||0.0006%|
|Related substances||Total: Not more than 1.0%
Individual: Not more than 0.5%
|E-isomer||Not more than 0.3%||0.18%|
|Organic volatile impurities||Conforms||Conforms|
Tamoxifen Citrate is anti-estrogen fertility inducer, the objects in dysfunctional uterine bleeding, polycystic ovary, menstrual disorders and drug-induced amenorrhea and other gynecologic diseases; It is used as a first line defense against breast cancer. Nolvadex or Tamoxifen citrate, a non-steroidal antiestrogen for oral administration, is commonly by athletes as a post cycle therapy drug to reduce or prevent the formation of excess estrogens that can lead to oily skin, acne, fluid retention, and gynecomastia.
In terms of dosing for combating gynecomastia that has begun to form, there is very little research. The limited research that does exist does point to the fact that doses of 20-40mgs per day are effective in treating the existing condition.
For use during post-cycle therapy users have anecdotally indicated that doses ranging between 20 and 40mgs per day are average. These doses have been shown to significantly raise levels of testosterone, luteinizing hormone and follicle stimulating hormone. Most users have reported when using tamoxifen citrate for their post-cycle therapy they will administer the drug for a minimum of three weeks. A maximum length has not necessarily been established due to the few side effects associated with the compound.
|Character||White crystalline powder.|
|Melting point||140-144 °C|
|Description||Nolvadex is the trade name for the drug tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties.|
|Usage||estrogen antagonist, antineoplastic|