Comprar 99.46% Purity Laboratory Tested Pramoxine Hydrochloride (pramoxina Hcl) Material anestésico local polvo crudo Con Discreto envío entrega rápida
Pramoxine Hydrochloride Powder Specification
| Producto |
Pramoxine Hydrochloride |
| Tests |
resultados |
Presupuesto |
| Descripción |
Polvo cristalino blanco |
White to almost white crystalline powder |
| Solubility |
Complies |
Freely soluble in water and in alcohol ,soluble in chloroform,very slightly soluble in ether |
| PH |
4.37 |
Acerca de 4.5 |
| IdentifIcation |
Complies |
A: By IR, To match with working standard |
| Complies |
B:By HPLC, To match with working standard |
| Complies |
do: A solution responds to the test for Chloride |
| Punto de fusion |
172.6℃～173.5℃ |
170℃～174℃ |
| Pérdida por secado |
0.18% |
≤1.0% |
| Residuos en ignición |
0.03% |
≤0.1% |
| Residual Solvents |
Not detected |
Toluene ≤0.089% |
| Not detected |
Ethanol ≤0.5% |
| 0.003% |
Petroleum ether ≤0.5% |
| 0.009% |
Acetone ≤0.5% |
| 0.006% |
Methanol ≤0.3% |
| Ensayo |
99.96% |
98.0%-102.0%(on the anhydrous basis) |
| Conclusión: Conforms to USP36 |
Pramoxine Hydrochloride Description
Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride.
During research and development, pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.
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