» Other Product » Local Anesthetic Powders » 99.5% Purity Pramoxine Hydrochloride (Pramoxine Hcl) Powder

99.5% Purity Pramoxine Hydrochloride (Pramoxine Hcl) Powder

  • Description

Buy 99.46% Purity Laboratory Tested Pramoxine Hydrochloride (Pramoxine Hcl) Powder Raw Local Anesthetic Material With Discreet Shipping Fast Delivery

 

Pramoxine Hydrochloride Powder Specification

Product Pramoxine Hydrochloride
Tests Results Specifications
Description White crystalline powder White to almost white crystalline powder
Solubility  

Complies

Freely soluble in water and in alcohol ,soluble in chloroform,very slightly soluble in ether
PH 4.37 About 4.5
IdentifIcation Complies A: By IR, To match with working standard
Complies B:By HPLC, To match with working standard
Complies C: A solution responds to the test for Chloride
Melting point 172.6℃~173.5℃ 170℃~174℃
Loss on drying 0.18% ≤1.0%
Residue on ignition 0.03% ≤0.1%
Residual Solvents Not detected Toluene ≤0.089%
Not detected Ethanol ≤0.5%
0.003% Petroleum ether ≤0.5%
0.009% Acetone ≤0.5%
0.006% Methanol ≤0.3%
Assay 99.96% 98.0%-102.0%(on the anhydrous basis)
Conclusion: Conforms to USP36

 

Pramoxine Hydrochloride Description

Pramocaine (INN and BAN, also known as pramoxine or pramoxine HCI) is a topical anesthetic used as an antipruritic. Chemically, it is p-n butoxyphenyl gammamorpholinopropyl ether hydrochloride.

During research and development, pramoxine hydrochloride stood out among a series of alkoxy aryl alkamine ethers as an especially good topical local anesthetic agent.Pharmacologic study revealed it to be potent and of low acute and subacute toxicity, well tolerated by most mucous membranes and of a low sensitizing index in humans. Like other local anesthetics, paramoxine decreases the permeability of neuronal membranes to sodium ions, blocking both initiation and conduction of nerve impulses. Depolarization and repolarization of excitable neural membranes is thus inhibited, leading to numbness.

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