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  • GnRH Peptide Gonadorelin 2mg 10mg

    Assay: 98%+ by HPLC
    Capacity: 2mg/vial, 10mg/vial
    Minimum order quantity(MOQ): 1 vial
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    • Description

    Buy GnRH Peptide Gonadorelin (2mg, 10mg / vial) Powder Online

     

    What is Gonadorelin? 

    Gonadorelin (also called Gonadorelin Acetate) is a synthetically produced gonadotropin-releasing hormone (GnRH).

    Gonadorelin primarily stimulates the synthesis and release of luteinizing hormone (LH) from the anterior pituitary gland. Follicle-stimulating hormone (FSH) production and release is also increased by gonadorelin, but to a lesser degree. In prepubertal females and some gonadal function disorders, the FSH response may be greater than the LH response.

     

    Gonadorelin Application

    Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function.

    Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use.

     

    Gonadorelin Basic Information

    Other Name: LH-RH, human, Gonadoreline, Gonadorelin Acetate
    Cas No. 71447-49-9; 33515-09-2
    Sequence:  Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
    Product Categories Amino Acid Derivatives; Peptide; API;
    Purity (HPLC):  98.0%min.
    Appearance:  White powder
    Molecular Formula:  C59H83N17O17
    Molecular Weight:  1302.39
    Single Impurity (HPLC):  0.5%max
    Amino Acid Composition:  ±10% of theoretical
    Peptide Content (N%):  ≥80.0%
    Water Content(Karl Fischer):  ≤8.0%
    Acetate Content(HPIC):  ≤10.0%
    Specific Rotation (20/D):  -55.0~-65.0°(c=1 1%HAc)
    MS (ESI):  Consistent
    Mass Balance:  95.0~105.0%

     

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