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Assay: 99.60% by HPLC
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|Product name||Articaine hydrochloride|
|CAS No.||23964-57-0||Outer Packing||25kg/drum|
|Production date||2019.01.08||Shelf life||2021.01.07|
|Items of analysis||Specification||Results|
|Appearance||A white or almost white crystalline power||A white crystalline power|
|Solubility||Freely soluble in water and in alcohol||Complies|
|Appearance of solution
|Solution should be clear||Complies|
|Related Substances||Impurity A ≤0.2%;Any other impurity ≤0.1%;Total of other impurities ≤0.5%||Not detected;0.08%;0.26%|
|Loss on drying||＜0.5%||0.09%|
|Resiue on ignition||≤0.1%||0.09%|
Articaine is a dental local anesthetic. It is the most widely used local anesthetic in a number of European countries and is available in many countries around the world.
The elimination of articaine is exponential with a half-life of 20 minutes. Since articaine is hydrolized very quickly in the blood, the risk of systemic intoxication seems to be lower than with other anesthetics, especially if repeated injection is performed.
The combination of articaine can be used for local or regional anaesthesia for dental procedures. Anaesthesia begins within six minutes and lasts for an hour. The half-life of articaine is approximately 1.8 hours. It is metabolised and then mainly excreted in the urine.